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Mark must overcome numerous obstacles, mostly weather-related, in order to get to the church to marry Elizabeth, who is stuck with both of her bickering, divorced parents. Abby has a major cold, but cannot leave the hospital, due to most of the nurses being at the wedding. Many patients come in to the ER from an accident involving a prison van; Luka and Carter clash over the treatment of an injured cop and a prisoner with a dislocated shoulder. While waiting for a flight to Vegas, Weaver (who wasn't invited to the wedding), strikes up a conversation with a friendly man. Chen misses her son. Cleo doesn't want to go to the wedding, because the bride is Peter's ex-girlfriend.

Mandy Freund, Arye Gross, Charles Hoyes, Tom Kiesche, J. Karen Thomas, Kirk B.R. Woller, Bob Boucher, Judith Drake, Ajgie Kirkland, Honey Lauren, Bob McClurg, Alex Kapp, Paul Freeman, Karimah Westbrook, Christopher Der Gregorian, Casey Biggs, Banji, Trisha Cruz, Randy Mulkey